Background.Although numerous risk factors for delayed graft function (DGF) have been identified, the role of ischemia-reperfusion\ninjury and acute rejection episodes (ARE) occurring during the DGF period is ill-defined and DGF impact on patient and graft\noutcome remains controversial. Methods. From1983 to 2014, 1784 kidney-only transplantations from deceased donors were studied.\nClassical risk factors for DGF along with two novel ones, recipientââ?¬â?¢s perioperative saline loading and residual diuresis, were\nanalyzed by logistic regression and receiver operating characteristic (ROC) curves. Results. Along with other risk factors, absence of\nperioperative saline loading increases acute rejection incidence (OR = 1.9 [1.2ââ?¬â??2.9]). Moreover, we observed two novel risk factors\nfor DGF: patientââ?¬â?¢s residual diuresis ââ?°Â¤500 mL/d (OR = 2.3 [1.6ââ?¬â??3.5]) and absence of perioperative saline loading (OR = 3.3 [2.0ââ?¬â??\n5.4]). Area under the curve of the ROC curve (0.77 [0.74ââ?¬â??0.81]) shows an excellent discriminant power of our model, irrespective\nof rejection. DGF does not influence patient survival (
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